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on understanding the mechanisms of protein synthesis and translational control in health and disease. The primary focus of the lab is to elucidate how ribosomes act as sensors of cellular stress and to discover the
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recent examples of our research include Jeong et al, Science 2023; Vessoni et al, JCB 2021, Munroe et al Hepatology 2020. This project will likely involve human stem cell differentiation assays, protein
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cardiovascular diseases. Currently, we are studying mitochondrial calcium signaling and how it is altered in heart, liver, and kidney failure. Our research employs techniques in molecular and cellular biology
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and/or gut infections. A robust B cell response is protective; however, sustained B cell activation can lead to chronic diseases like cancer and/or autoimmunity. The project involves investigating
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Research and Training Institute (CVRTI), is seeking a motivated postdoctoral fellow to work on projects that bridge from basic cell biology to small and large animal model systems. The focus of the lab is
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disease. The primary focus of the lab is to elucidate how ribosomes act as sensors of cellular stress and to discover the ribosome-mediated quality control and signaling pathways that govern cell fate
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, the cell biology of photoreceptors and hair cells, and potential treatments. We utilize mouse models and various approaches in molecular and cellular biology, biochemistry, omics, bioinformatics