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. Clinical studies have demonstrated that hereditary neuropathies can also involve muscle pathologies, complicate diagnosis and hamper therapy development. We have developed advanced in vitro cell models
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. Clinical studies have demonstrated that hereditary neuropathies can also involve muscle pathologies, complicate diagnosis and hamper therapy development. We have developed advanced in vitro cell models
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team of Prof. Seppe De Schepper investigates how peripheral immune signals influence brain health and disease. We focus on tissue-resident macrophages and immune cell trafficking from periphery to brain
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, ultimately triggering neuroinflammation. The PhD student will help uncover the molecular and cellular pathways linking the allergic gut to the inflamed brain, and how these pathways shape disease risk later in
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well as the available public data suggest mechanisms involving genetic, epigenetic and chromatin organisation factors governing the cell-type specific response to ARS mutations. Therefore, an integrative genome-wide cis
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, and poor prognosis of CRC. Adenocarcinomas also overexpress transmembrane mucins to exploit their role in promoting tumour cell death resistance. Furthermore, mucins undergo extensive splicing. Mucins
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the imec-Vision Lab (image reconstruction, processing, and analysis), the Bio-Imaging Lab (preclinical neuro-MRI), and the Laboratory of Cell Biology and Histology (cell biology and advanced microscopy
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towards cancer and has been linked to initiation, progression, and poor prognosis of colorectal cancer. Adenocarcinomas also overexpress transmembrane mucins to exploit their role in promoting tumour cell
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the preparation and defence of a PhD thesis in the field of Medical Sciences. More specific, you will work on the validation of predictive peptide biomarkers to classify non-small cell lung cancer (NSCLC) patients