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. Clinical studies have demonstrated that hereditary neuropathies can also involve muscle pathologies, complicate diagnosis and hamper therapy development. We have developed advanced in vitro cell models
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. Clinical studies have demonstrated that hereditary neuropathies can also involve muscle pathologies, complicate diagnosis and hamper therapy development. We have developed advanced in vitro cell models
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well as the available public data suggest mechanisms involving genetic, epigenetic and chromatin organisation factors governing the cell-type specific response to ARS mutations. Therefore, an integrative genome-wide cis
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team of Prof. Seppe De Schepper investigates how peripheral immune signals influence brain health and disease. We focus on tissue-resident macrophages and immune cell trafficking from periphery to brain
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, ultimately triggering neuroinflammation. The PhD student will help uncover the molecular and cellular pathways linking the allergic gut to the inflamed brain, and how these pathways shape disease risk later in