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state of Rhineland-Palatinate. Our research focuses on the biology of the cell nucleus and ranges from the molecular level to systems and computational approaches. Researchers at IMB are supported by
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A 3-year fully funded PhD stipend for studying the gene-regulatory mechanisms that control cancer biology at single-cell resolution is available in the group of Associate Professor Rasmus Siersbæk
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, osteosarcoma) cell and time of origin is debated but experimental studies in different models suggest possible in utero induction with postnatal initiation similar to leukaemia. In Ewing sarcoma, FET::ETS gene
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supervising studies that involve in vitro assays and in vivo mouse tumor models to understand mechanisms of immunotherapy resistance, exploration of pathways involved in signal transduction in different T cell
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signalling, raising the possibility of shared molecular mechanisms. Project Aims This PhD project will focus on investigating the fibrotic behaviour of cells isolated from glaucoma patients of different ethnic
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supervising studies that involve in vitro assays and in vivo mouse tumor models to understand mechanisms of immunotherapy resistance, exploration of pathways involved in signal transduction in different T cell
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PhD Studentship: Dissecting the Molecular Architecture and Function of LMTK3 as a Therapeutic Target
; University of Sussex | The City of Brighton and Hove, England | United Kingdom | about 1 month agomechanisms underpinning LMTK3's multifaceted role in cancer biology. By employing a multidisciplinary approach combining structural biology, biochemistry, and cell biology, this research aims to provide novel
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supportive and friendly team, you will learn how to design and perform experiments that interrogate the molecular and cellular mechanisms regulated by ADAM15 and ADAM12 in glioma, employing cellular
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., Cell Metabolism, 2023; Leung et al., Science Translational Medicine, 2022; Seelbinder et al., Nature Communications, 2023). MBD is currently coordinating the EU-funded consortium MiCCrobioTAckle
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manufacturing using single cell omicsSupervisors: Colin Clarke and Niall BarronAbout the project: The study of cellular biology has been transformed by single cell analysis. Rapid technological advances in areas