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of Dr. Laurent HEUX as part of the WALLMAT project of the PEPER B-BEST program, which focuses on the valorization of polymers derived from biomass and involves six different laboratories (https://www.pepr
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assays: Establish cultures of host phytoplankton and their parasitoids to investigate infection dynamics under controlled conditions. Single‑cell genomics: Apply single‑cell sequencing to characterize
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genetic screens in lung cancer cell models Culture and manipulate human lung cancer cell lines and organoids, including transfections and viral transductions Perform drug sensitivity assays in vitro and
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) to perform innovative research in community health and biomedicine. The Department of Molecular, Cellular, and Biomedical Sciences (MCBS) was formed through the merger of several basic science departments and
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on genomic structural rearrangements. We use computational and experimental approaches including WGS, single-cell, and long-read sequencing together with chromatin conformation techniques to understand
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, treatment, and prevention of human diseases (e.g., Li et al., Nature Metabolism, 2024; Ni et al., Cell Metabolism, 2023; Leung et al., Science Translational Medicine, 2022; Seelbinder et al., Nature
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supervising studies that involve in vitro assays and in vivo mouse tumor models to understand mechanisms of immunotherapy resistance, exploration of pathways involved in signal transduction in different T cell
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supervising studies that involve in vitro assays and in vivo mouse tumor models to understand mechanisms of immunotherapy resistance, exploration of pathways involved in signal transduction in different T cell
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., Cell Metabolism, 2023; Leung et al., Science Translational Medicine, 2022; Seelbinder et al., Nature Communications, 2023). MBD is currently coordinating the EU-funded consortium MiCCrobioTAckle
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manufacturing using single cell omicsSupervisors: Colin Clarke and Niall BarronAbout the project: The study of cellular biology has been transformed by single cell analysis. Rapid technological advances in areas