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mechanisms, with a track record of creative research in molecular biology, cell biology, genomics, imaging approaches and/or bioinformatics. If selected for this position, you will be expected to: Develop and
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of nuclear structure and function. Current Opinion in Cell Biology 26, 10-18. Hazra, R., Brine, L., Garcia, L., Benz, B., Chirathivat, N., Shen, M.M., Wilkinson, J.E., Lyons, S.K., and Spector, D.L. 2022
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hematopoietic cell development and hematologic cancers. Based on these basic mechanistic insights, the Laboratory is building innovative therapeutics to treat hematopoietic cancers that are currently without
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Degradation (TPD) therapeutic strategies to abrogate or rewire cancer cell signaling. We have recently established a new discovery platform to expand the landscape of TPD E3 ligases and targeting modalities
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organ 3D imaging at single cell resolution of the disease (PMID 34788609). This now allows them to map and functionally probe the neuro-metastatic interface (reviewed in 32302564). The work is a close