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tract, how immunity develops in early life, and how it goes awry in devastating inflammatory diseases such as necrotising enterocolitis and inflammatory bowel disease. Spatial ‘omics and single cell
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situ/operando experiments and associated cell design is desirable. Familiarity with one or more of the following techniques is highly desirable: X-ray and neutron diffraction, computational chemistry
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situ/operando experiments and associated cell design is desirable. Familiarity with one or more of the following techniques is highly desirable: X-ray and neutron diffraction, computational chemistry
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, penetration and toxicity of novel metallodrug-coated gold nanoparticles in a 3D-cell culture model of head and neck cancer. This is a highly inter-disciplinary project involving collaboration between Dr Nik
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, see: https://www.cell.com/cell-metabolism/pdf/S1550-4131(19)30248-7.pdf https://pubmed.ncbi.nlm.nih.gov/38879728/ Key responsibilities and duties: ¿ Study ethical approval application
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biology or a related subject. You should have a competence in cell biology and basic molecular biology techniques. The ideal candidate should be organised, highly motivated and able to work independently as
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fluorescence-lifetime detection (Fast-FLIM) and temporal focusing. This instrument will deliver quantitative, sub-second imaging of live three-dimensional cell-culture and organoid models, advancing fundamental
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Utilising multiple cell types found in and around the kidney, treated to recapitulate the late-stage inflammation of diabetic nephropathy, this project will investigate how sodium glucose
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focuses on understanding how tumour cell plasticity and dynamic cell state transitions drive resistance, and aims to identify actionable vulnerabilities that could inform future therapies. You will work
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, see: https://www.cell.com/cell-metabolism/pdf/S1550-4131(19)30248-7.pdf https://pubmed.ncbi.nlm.nih.gov/38879728/ Key responsibilities and duties: Study ethical approval application. Study design