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Field
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functional properties and mechanisms of human Induced Pluripotent Stem Cell (iPSC) derived cortical neuronal networks in cortical organoids and planar cultures. Techniques used will include
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explore the cell biology, biochemistry and evolution of the Starship transposons in plant pathogenic fungi. We are seeking creative and ambitious scientists to lead any of the three following research
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research focuses on two areas: (1) how epigenetic memory—via Polycomb silencing and DNA methylation—is established and maintained, and (2) pattern formation in sub-cellular systems, particularly crossover
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disease. Together with other members of the team, the post-holder will design parallel tasks for rodents and humans and apply comparable analytical approaches to data across species. Cell and circuit
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situ/operando experiments and associated cell design is desirable. Familiarity with one or more of the following techniques is highly desirable: X-ray and neutron diffraction, computational chemistry
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situ/operando experiments and associated cell design is desirable. Familiarity with one or more of the following techniques is highly desirable: X-ray and neutron diffraction, computational chemistry
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analysis of genomic and related data and will depend on good mechanistic understanding of cellular processes involved in genome replication, damage tolerance and repair. Analyses will entail the development
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tract, how immunity develops in early life, and how it goes awry in devastating inflammatory diseases such as necrotising enterocolitis and inflammatory bowel disease. Spatial ‘omics and single cell
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, penetration and toxicity of novel metallodrug-coated gold nanoparticles in a 3D-cell culture model of head and neck cancer. This is a highly inter-disciplinary project involving collaboration between Dr Nik
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, see: https://www.cell.com/cell-metabolism/pdf/S1550-4131(19)30248-7.pdf https://pubmed.ncbi.nlm.nih.gov/38879728/ Key responsibilities and duties: ¿ Study ethical approval application