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engineered mouse models for the depletion of different CAF populations, in vitro three-dimensional pancreatic tumour organoid/fibroblast co-culture models, CRISPR-based technologies, bulk and single-cell RNA
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stacking error and removes the options for easy disassembly for repair, replace or recycle. In this project modification of the cell end cap design is to be investigated through FE analysis, prototype build
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PhD Opportunities in Molecular and Cellular Biology School of Biosciences PhD Opportunities Self Funded View DetailsApply Online
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The development of electric vertical take-off and landing (eVTOL) vehicles is one of the best solutions for solving transportation problems such as air pollution, road congestion, and long commute times. Lithium-ion batteries due to their high energy density, long lifetime, fast charging, wide...
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chromatin profiling methods along with CRISPR/Cas9-meduated cell line engineering and various animal models. You will study the effects of the activation or depletion of chromatin-modifying enzymes using
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methodologies to detect and deconvolute the mutational processes associated with CIN [1], leveraging single-cell DNA sequencing understand CIN heterogeneity [2], and development and implementation of machine
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Gregory Hamm (AstraZeneca). Project details The tumour immunity cycle involves cyclical trafficking of T cell subsets between the tumour and lymphoid organs. While current immunotherapy has focused on re
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targets the development of advanced coatings to prevent cell-to-cell propagation during runaway events. It combines experimental studies, numerical modelling, and real-world burner rig testing, culminating
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stability and how these impact cell state changes. Recently, we have demonstrated the profound impact of G-quadruplexes on the transcription of cancer-related genes and in super-enhancer function. At the core
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. The effect of hydrogen gas on coating performance and the resulting corrosion behaviour will be assessed, supported by hydrogen permeation measurement using a novel diffusion cell set-up. The Zinc composition