-
both sites. The project sits at the interface of cell line engineering, protein science and machine learning and you will receive advanced training in these areas while developing methods to accelerate
-
technologies, bulk and single-cell RNA-sequencing, flow cytometry, multiplex immunofluorescence, and standard molecular biology and biochemistry techniques. A computational component may also be available
-
and can survive. Combining TAT and DDR inhibitors thus has the potential to convert this sub-lethal DNA damage into cancer cell killing. This project will explore the effects of radioligand therapies
-
chromatin profiling methods along with CRISPR/Cas9-meduated cell line engineering and various animal models. You will study the effects of the activation or depletion of chromatin-modifying enzymes using
-
processes associated with CIN [1], leveraging single-cell DNA sequencing understand CIN heterogeneity [2], and development and implementation of machine learning and AI models to imaging data [3]. The student
-
Gregory Hamm (AstraZeneca). Project details The tumour immunity cycle involves cyclical trafficking of T cell subsets between the tumour and lymphoid organs. While current immunotherapy has focused on re
-
We are looking for a full-time Research Assistant in Dr Fengzhu Xiong's lab at the Gurdon Institute, University of Cambridge. The successful candidate will be involved in studies of collective cell
-
stability and how these impact cell state changes. Recently, we have demonstrated the profound impact of G-quadruplexes on the transcription of cancer-related genes and in super-enhancer function. At the core
-
cancer is dynamic and dependent on ASCL1. Nat Cancer. 2024 Nov;5(11):1641-1659 https://pubmed.ncbi.nlm.nih.gov/39394434/ ASCL1 activates neuronal stem cell-like lineage programming through remodeling
-
, optoelectronic, neuromorphic; Scale-up and Systems - Nanomanufacturing, cellular manufacturing, sensors /actuators, bioelectronics, IoT, theranostics; Frontiers in Nano-Metrology - in-situ nanometrology, electron