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Project Overview This 5-year BBSRC supported project is a highly multi-disciplinary effort between biology and engineering groups at the University of Oxford to advance cell-based assays
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. You'll use advanced cellular immunology techniques to conduct deep phenotypic and functional characterisation of regulatory T cells (Tregs), establishing their relationship with treatment responses and
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). About the role The project's primary goal is to investigate how low-dose IL-2 affects the neuro-inflammatory process. You'll use advanced cellular immunology techniques to conduct deep phenotypic and
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development of computational approaches to integrate multi-omics data from patient samples, including DNA methylation, histone modifications, single-cell transcriptomics and chromatin accessibility. You will
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have recently highlighted the importance of the FAT1 gene during carcinogenesis (Lu et al, Nature Cell Biology 2025; Lu and Kanu, Nature Cell Biology 2025). We strive to understand the molecular
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myeloproliferative neoplasms (MPNs). You will take a lead role in conducting wet lab experimentation, applying state-of-the-art single-cell multiomic approaches and functional genomic screens to patient-derived
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experimentation, applying state-of-the-art single-cell multiomic approaches and functional genomic screens to patient-derived samples and disease models. Working closely with a dynamic and multidisciplinary team
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approaches including targeted genetic murine models, primary cell culture and analysis, multi-omics and bioinformatics. The biological focus will be on vascular biology, immune cell function and metabolism
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Claudia Monaco’s research group at the Kennedy Institute of Rheumatology. In this role, you will apply single cell biology and cell signalling techniques combined with in vivo and in vitro models
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focused on integrating synthetic biology, AI, and multi-omics technologies to decode and design gene expression regulation for human cell engineering. About the role We are looking for an ambitious and