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state. The project will specifically investigate the role of endogenous retroelements in this context. Immune-functional consequences will be studied using in vivo mouse models, and in cell culture
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, extension is sought) Contract:TV-L Your tasks Molecular laboratory work with 2D and 3D cell culture models Experimental design, data analysis and interpretation Publishing research findings in peer-reviewed
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variants on human traits and single-cell readouts. Our research group is pioneering computational methods for deciphering molecular variation across individuals, space, and time. We have a track record in
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analyses. Three-dimensional cell cultures are important to enable realistic cell environments for disease modeling and to analyze cell interactions. This project will address the important questions of how
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of biochemistry, cell and structural biology, and biomedical research. With approximately 30 scientific departments and research groups and about 750 employees, the MPIB is one of the largest institutes of the Max
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in operating a high-end microscope (e.g., life cell, confocal microscopy or multiphoton) are required. WE OFFER: Career development in a multidisciplinary and committed research team. Mentorship
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Institute for Translational Brain Research (HITBR) ). Research will focus on building next-generation organoid and assembloid models combined with single-cell perturbation screens to monitor cell fate
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interaction analysis and single-cell approaches to unravel regulatory mechanisms of heart function and disease. CRISPR-based functional genomics will allow you to explore and steer the regulatory mechanisms
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an attractive drug target. The position is funded by an Emmy Noether DFG grant and aims to combine single-molecule localization methods and cell biology to decipher the stoichiometry and dynamics of plexin
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-dimensional cell cultures are important to enable realistic cell environments for disease modeling and to analyze cell interactions. This position will address the question of how one can develop minimally