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project focusing on a long-standing and fascinating question : « what makes our brain cells human ? » (see our recent work : Hecker et al. Science 2025; Libé-Philippot et al. Cell 2023; Vanderhaeghen and
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project dedicated to decoding early human embryo development through cutting-edge stem cell-based embryo models, single-cell omics, with a focus on X-chromosome inactivation and cell fate. The project
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to unravel how plants control gene expression across different tissues and stress conditions by combining single-cell genomics, artificial intelligence, and synthetic biology. Apart from shedding light on
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and stress conditions by combining single-cell genomics, artificial intelligence, and synthetic biology. Apart from shedding light on the fundamental aspects of transcriptional control, this project
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, proteomics, metabolomics, single cell and/or genotyping data.Microbiology techniques is a plus but not required.Experience in molecular biology techniques for processing and analysis of DNA and RNA is a plus
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, transcriptomics, proteomics, metabolomics, single cell and/or genotyping data. Microbiology techniques is a plus but not required. Experience in molecular biology techniques for processing and analysis of DNA and
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developmental biology, cell biology and evolutionary biology. We like to implement novel omics technologies such as single cell approaches and chemical biology to help us answering our biological questions
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method, can engineer thousands of defined mutations in parallel in a single test tube in yeast. Strains are tagged by DNA barcodes, allowing to efficiently track mutations in cell populations during
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method, can engineer thousands of defined mutations in parallel in a single test tube in yeast. Strains are tagged by DNA barcodes, allowing to efficiently track mutations in cell populations during
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question: « what makes our brain human ? » (Vanderhaeghen and Polleux, Nat. Rev. Neurosci. 2023). We combine cutting-edge approaches such as pluripotent stem cell models of human corticogenesis, human-mouse