7 cell-surface-display PhD positions at International PhD Programme (IPP) Mainz in Germany
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or neural memory. Activities and responsibilities The research group of Johannes Mayer offers the following PhD project: Dendritic cells in the skin perform diverse functions. Acting primarily as sentinel
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to combat extracellular particles, by removing or encapsulating them. Main orchestrators are T helper 2 (Th2) and innate Lymphoid cells, which secreting cytokines including IL-4, IL-5, IL-9, and IL-13
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translocases have been shown to regulate R-loop levels in cells. In recent years, R-loops have been recognized as a major cell-intrinsic source of genomic instability, and dysregulation of R-loop processing is
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between quiescence and activation allows the hematopoietic stem cells (HSC) to continuously replenish all mature blood cells in homeostasis and in response to challenges. However, upon aging, HSC become
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immunogenicity of RNA to modulate essential cell programs like cell proliferation, differentiation, and stress response. Pathological changes in the epitranscriptome are seen as a new cancer hallmark: an
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discriminated against all other nuclear RNAs? How does the cell ensure that only fully matured mRNAs are exported? How are faulty mRNAs and transcription byproducts targeted for degradation? At the core of mRNA
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epigenetic memory in cells and can be transmitted across generations, raising the possibility that DNA damage can reshape the epigenome in damaged cells and affect their descendants. Due to the complexity