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will develop and benchmark approaches that infer copy-number changes and CIN dynamics directly from single-cell RNA-seq, then connect these CIN signals to (i) the molecular programs that allow tumor
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of two former supervisors A complete publication list (can be included in your CV) A copy of your diploma (PhD or equivalent) We warmly welcome your application! Where to apply Website https://lu.varbi.com
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-cell transcriptomics and modern statistical/AI methodology to address this gap using in-house developed cell atlases. We will develop and benchmark approaches that infer copy-number changes and CIN
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on cells influence cancer development and progression. My work aims to better understand how cancer cells respond to stress during disease progression and how these responses contribute to invasion
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; https://linkinghub.elsevier.com/retrieve/pii/S1937644817300825)vol. 335, pp. 41–84. What are the signals that determine innate immune memory? Supervisor: Ruaidhrí Carmody Project description: Cells
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independently as well as in collaborative research efforts. Required Qualifications PhD in Cell Biology, Developmental Biology, Biomedical Engineering, or a related field Proficiency in cell culture techniques
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for cellular proliferation and the faithful transmission of genetic information to daughter cells. However, replication forks are constantly challenged by a wide range of intrinsic and extrinsic stressors
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cutting-edge project applying CRISPR to dissect the consequences of copy-number alterations in iPS cells. This project focuses on 8p syndrome, a developmental disorder caused by a complex rearrangement on
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: 1 year Appointment Start Date: Flexible Group or Departmental Website: http://www.sheltzerlab.org (link is external) How to Submit Application Materials: Email your application to Dr. Sheltzer Does
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separation. Lab Chip 20: 614-625. Hosseini SM & Feng JJ (2012). How malaria parasites reduce the deformability of infected red blood cells. Biophys J 103: 1–10. https://doi.org/10.1016/j.bpj.2012.05.026 Mott A