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geroscience research program focused on the mechanisms underlying aging, epigenetics, mitochondria, metabolism, inflammaging, cell death and senescence, chronic pain, healthspan, and functional capacity (both
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, SCALE develops innovative tools to explore, map, and simulate the inner architecture of cells. This interdisciplinary work expands our understanding of central biological processes and diseases – from
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disease states involving mtDNA defects, we are working to elucidate how our cells normally ensure the stable maintenance of mtDNA and how mtDNA defects are communicated to the rest of the cell. The aim
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actively influence cancer development by signaling to tumor cells and promoting tumor growth. A central mechanism involves neuron-to-glioma synapses, which transmit neuronal activity to glioblastoma cells
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cells) - Synchrotron measurements (e.g., diffraction, tomography, inelastic x-ray scattering, and/or absorption spectroscopy) - Measurements at X-ray Free Electron Laser (XFEL) facilities - Pulse-echo
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ribosome-mediated quality control and signaling pathways that govern cell fate decisions. The dysregulation of these surveillance mechanisms is linked to ribosome dysfunction, loss of proteostasis, and human
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minutes, and published on https://apply.uc.pt/ . VII.IX -Jury Composition: President: Ana Sofia Bregieiro Eulálio, Principal Investigator, Center for Neuroscience and Cell Biology Effective Members: Miguel
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statistics, policies, and procedures related to campus safety. Go here to review: https://safety.temple.edu/reports-logs/annual-security-report You may request a copy of the report by calling Temple
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description In recent years, research has shown that neurons actively influence cancer development by signaling to tumor cells and promoting tumor growth. A central mechanism involves neuron-to-glioma synapses
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and molecular biology will be valued, namely: different cell culture models, particularly in tumorigenic models, , cellular transfection, cell viability assays, luminescence and/or fluorescence assays