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Field
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variety of methods—from translational in vitro-studies using additively manufactured materials and cultured cells, to clinical research including large-scale randomized trials. Our translational research is
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of metabolic dysfunction. What you will do This PhD project aims to study a novel lipid signaling pathway in adipocytes, cells specialized in lipid uptake, storage and metabolism, that play a central role in
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both sites. The project sits at the interface of cell line engineering, protein science and machine learning and you will receive advanced training in these areas while developing methods to accelerate
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of equipment – which of course includes AI. Meanwhile we are pushing the limits of applied mathematics, for example mapping out disease processes using single cell data, and using mathematics to simulate
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, hardware prototyping, compiler design, simulation and emulation tools, as well as cybersecurity, reliability, and system verifiability. The objective of this PhD project is to develop a gain-cell memory
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Instituto de Investigação e Inovação em Saúde da Universidade do Porto (i3S) | Portugal | 11 days ago
microfluidic devices, at all levels: design in CAD, SU8 to epoxy mold copy, PDMS preparation, PDMS casting; Experience with cellular/neuronal cultures on PDMS-based microfluidic devices; Proficiency, and full
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Instituto de Investigação e Inovação em Saúde da Universidade do Porto (i3S) | Portugal | 25 days ago
achieved. The candidate will develop research work focusing on the synthesis of biodegradable dendrimers for the complexation of neurotoxin-derived proteins and subsequent targeted delivery to neuronal cells
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of chromatin and protein assemblies in the cell nucleus, and how this organization is changed upon infection. Our group thrives on scientific curiosity and the free exploration of ideas sparked by ongoing
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at cell membranes; Apply machine-learning models trained on simulation data to study how lipid composition and genetic variation influence the conformational and phase properties of membrane-associated
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Instituto de Investigação e Inovação em Saúde da Universidade do Porto (i3S) | Portugal | about 1 month ago
of the bHLH family (such as ASCL1) that function as master regulators of neuronal differentiation, and are thus often deployed in neuronal reprogramming protocols (e.g., Raposo et al, 2015, Cell Reports