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CD8+ T cell clones specific for HLA-I-restricted neoepitopes carrying recurrent driver mutations in cancer, and cloning their TCRs to investigate the epitope generation in cancer cells; (iii
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technologies (bulk and single-cell RNA-seq) and omics analysis Prior experience in flow cytometry Prior experience in 3D cell culture Downloading a copy of our Job Description Full details of the role and the
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Therapy and Regenerative Medicine acts as a focus for cutting-edge stem cell research taking place across King’s and its partner NHS Trusts, as part of King’s Health Partners. Our research environment is
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strengths in laboratory-based enquiry using molecular genetics, metagenomics, biochemistry, cell biology, bioinformatics and structural biology, with rich clinical resources in microbiology, virology
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cytometry Prior experience in advanced sequencing technologies (bulk and single-cell RNA-seq, spatial transcriptomics) and omics analysis Downloading a copy of our Job Description Full details of the role and
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induced pluripotent stem cell (hiPSC) lines. The successful candidate will be responsible for generating brain organoids and assembloids, and to conducting a comprehensive analyses comparing wildtype and
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focused on integrating synthetic biology, AI, and multi-omics technologies to decode and design gene expression regulation for human cell engineering. This role is based in Randall Centre for Cell
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following skills and experience: Essential criteria PhD in cardiovascular Biochemistry/Physiology Strong background in biochemistry and molecular biology Tissue/cell culture experience Culturing neonatal rat
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Formstone (see Panousopoulou et al. J. Cell Sci. 2016 (https://doi.org/10.1242/jcs.180703) and Prof. Philippa Francis-West (Mao et al. Nature Comms. 2016 (https://doi: 10.1038/ncomms11469 and Prof. Philippa
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regulators that make the muscular abdominal wall, dermis and epidermis grow around the viscera. The work will be in close collaboration with Dr. Caroline Formstone (see Panousopoulou et al. J. Cell Sci. 2016