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CD8+ T cell clones specific for HLA-I-restricted neoepitopes carrying recurrent driver mutations in cancer, and cloning their TCRs to investigate the epitope generation in cancer cells; (iii
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technologies (bulk and single-cell RNA-seq) and omics analysis Prior experience in flow cytometry Prior experience in 3D cell culture Downloading a copy of our Job Description Full details of the role and the
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Therapy and Regenerative Medicine acts as a focus for cutting-edge stem cell research taking place across King’s and its partner NHS Trusts, as part of King’s Health Partners. Our research environment is
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to Grade 6. Desirable criteria Experience of working with clinical trial samples under GCLP guidelines Experience of analysing complex single-cell data sets Downloading a copy of our Job Description Full
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strengths in laboratory-based enquiry using molecular genetics, metagenomics, biochemistry, cell biology, bioinformatics and structural biology, with rich clinical resources in microbiology, virology
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cytometry Prior experience in advanced sequencing technologies (bulk and single-cell RNA-seq, spatial transcriptomics) and omics analysis Downloading a copy of our Job Description Full details of the role and
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induced pluripotent stem cell (hiPSC) lines. The successful candidate will be responsible for generating brain organoids and assembloids, and to conducting a comprehensive analyses comparing wildtype and
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focused on integrating synthetic biology, AI, and multi-omics technologies to decode and design gene expression regulation for human cell engineering. This role is based in Randall Centre for Cell
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following skills and experience: Essential criteria PhD in cardiovascular Biochemistry/Physiology Strong background in biochemistry and molecular biology Tissue/cell culture experience Culturing neonatal rat
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Formstone (see Panousopoulou et al. J. Cell Sci. 2016 (https://doi.org/10.1242/jcs.180703) and Prof. Philippa Francis-West (Mao et al. Nature Comms. 2016 (https://doi: 10.1038/ncomms11469 and Prof. Philippa