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discovery and basic research to clinical translation. The postdoc fellow will be part of the Organs-on-Chip Technologies Lab (Prof. O. Guenat), which integrates microfluidic engineering with advanced cell
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the Department of Biomedicine at Mattenstrasse 28, 4057 Basel. Project: The aim of the project is to elucidate molecular intra- and extracellular mechanisms of signaling modulating myeloid cells’ immune
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remodeling and immune cell dynamics in chronic obstructive pulmonary disease (COPD). Job description You will Collaborate with partners in Bern to develop multi-compartment organ-on-chip systems integrating
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. • Perform a range of cell biology techniques, including primary cell isolation and culture, and conduct metabolic functional assays following gene silencing or overexpression. • Design and optimize sample
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, 4057 Basel. Project: Main focus: Targeting cell surface receptor signaling by newly designed covalent, PPI and allosteric inhibitors within an Innosuisse-funded project aiming to open a path to lead
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the successful candidate is the Department of Biomedicine at Mattenstrasse 28, 4057 Basel. Project: Main focus: Targeting cell surface receptor signaling by newly designed covalent, PPI and allosteric inhibitors
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compounds in biophysical and cell-based assays. Contribute to the teaching and supervision of junior researchers in the group. Profile We are looking for a candidate with an intrinsic interest in peptide
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to be removed surgically. This formation of bone in soft tissue is the result of an osteoinductive process during which stem cells are differentiated into bone cells. This property is essential to treat
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colonizing the intestine, it is permeable for essential nutrients while serving as a protective barrier to prevent microbial translocation. A tight balance between the intestinal epithelium, immune cells in
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contribute include: In vivo single-cell CRISPR perturbation screens CRISPR perturbation screens, such as Perturb-seq, are transforming how we study gene function at scale. We recently developed an AAV-based