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include identifying relevant molecular targets, linking cellular mechanisms and defects to disease phenotypes, and small molecule screening to identify therapeutics. Understanding vascular mural cell
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identified previously unrecognized cell-intrinsic mechanisms that regulate replisome dynamics and fork speed, establishing replisome velocity control as a key genome surveillance strategy (PMIDs: 29123070
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multidisciplinary clinical and translational research team focused on advanced multi-omics-based trials in colorectal cancer. The successful candidate will support the analyses of single-cell and spatial
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and molecular mechanisms underlying phenotypic variability in quiescent cell populations and their impact on adaptation, antifungal resistance, and population dynamics. The successful candidate will
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. The specific goal of this work is to unravel the molecular mechanisms of blood cell development using state-of-the-art technologies such as CRISPR screens, proteomics, and multi-omics approaches. About you: You
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from the lab has identified previously unrecognized cell-intrinsic mechanisms that regulate replisome dynamics and fork speed, establishing replisome velocity control as a key genome surveillance
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approaches at the interface between cell biology and mechanics, including advanced microscopy on living cells, cell biology (mammalian cell culture, transfection, molecular biology...) and micromanipulation
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will continue to investigate human brain development with a focus on stem cell lineages and synaptic diversity. See https://scholar.google.com/citations?user=09RosEoAAAAJ (link is external) for a
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a Mixed Ionic Electronic Conductor (MIEC). Aside from all the degradation phenomena activated upon operation [2], the cell is also submitted to various mechanical loading inducing a damage in the
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postdoctoral position within the ERC-2024-STG-funded project 1101165141-MANAGE HSC. This project combines stem cell and stem cell niche biology, bone marrow/niche engineering, and cell mechanics to investigate