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of this cell signalling pathway in aging remains to be established. Likewise, the cellular process(es) implicated in stem cell aging remain to be elucidated. This project consists in uncovering the mechanisms by
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criteria The postdoctoral researcher will: • Study the intricate cell cycle regulatory mechanisms of Plasmodium falciparum using advanced omics techniques, including single cell transciptomics, reverse
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PDAC tumours, which are mechanically extremely stiff. This project will investigate the role of Ect2 mechano-sensing in pancreatic cancer cells and patient tumours. Specifically, this project aims to: 1
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achieved 1) biochemically, via networks of interacting polarity proteins, 2) mechanically, via active transport of components from one side of the cell to another, or 3) mechanochemically, by the integration
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investigating the differences and similarities in cell cycle dysregulation between different cancer types. For more information please visit https://www.barrlab.com , see this article , or contact Alexis Barr
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that the toxin induces DNA damage responses in cultured cells that activates a senescence tumour suppressor mechanism (https://doi.org/10.1038/s41467-019-12064-1). Cells undergoing toxin-induced senescence undergo
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research on Duchenne Muscular Dystrophy with an emphasis on immune mechanisms involved in driving fibrosis versus regeneration and identifying and targeting barriers limiting efficacy of dystrophin
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programme Is the Job related to staff position within a Research Infrastructure? No Offer Description Workplace description A vacant position is available in the Cell, Tissue and Organ Engineering research
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conditions such as mechanical stress, low oxygen, and other environmental pressures. By combining concepts from cell biology, biophysics, and cancer research, my work seeks to uncover general principles
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combining research in cell biology, genetics, epigenetics, immunology, soft matter physics, organic chemistry, and medicinal chemistry. It brings together more than 3,800 researchers, doctors, clinicians