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of maladaptive innate immune pathways in neuronal stress and death, and (2) examine how mito-nuclear retrograde signaling contributes to microglial dysfunction and senescence in Alzheimer’s disease and related
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death. The role of NLR genes in these processes has been thoroughly described for plants and animals, but how they contribute to the fungal immune system is unexplored. Fungal NLR genes also show hugely
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Hirszfeld Institute of Immunology and Experimental Therapy Polish Academy of Sciences | Poland | 3 months ago
of various synthetic and natural substances, peptides, and antibodies. Investigation of signalling pathways leading to cell death is required. Laboratory experience in eukaryotic cell culture and functional
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bioinformatics. The main responsibilities include: High-throughput sequencing: Applying long-read sequencing technologies (Oxford Nanopore) to quantify DVG populations in cells and virions without PCR bias (Direct
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death, cancer, toxicology, environmental exposures), Zhi-Min Yuan (genetic engineered mouse models, p53, lung fibrosis). Together, we investigate mechanisms of disease that arise from environmental
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: connexin dysfunction in astrocytes, a type of support cell in the brain and spinal cord. Astrocytes play a vital role in maintaining motor neuron health, but when they malfunction, they can become toxic and
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, research, and clinical care. For more information about the Department of Pediatrics, please visit: http://medicine.utah.edu/pediatrics/ . The University of Utah offers a comprehensive benefits package
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and 3D animal cell culture; c) Candidates must be enrolled in a PhD or in a non-academic degree course integrated in an educational project of a Higher Education Institution in the academic year 2025
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Investigating Roles for C9orf72 in Regulating FIS1-mediated Cell Death and Survival School of Biosciences PhD Research Project Self Funded Dr C Guo, Dr Kurt de Vos Application Deadline
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specific emphasis on sudden cardiac death. Selected candidate will be leading the animal studies, conducting electrophysiology experiments, including those requiring experience with patch clamp technique