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of Dr. Andrew Davidson as part of a recently awarded Wellcome CDA. You will contribute to projects on understanding how cell death contributes to tumourigenesis using Drosophila combined with live
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studies have explored the mechanistic impact of Staufen1 in a wide variety of cell functions ranging from cell growth to cell death, as well as in various disease states. This PhD project aims to identify
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., Goossens, S. and Berx, G. (2025). Development and validation of a high-throughput screening pipeline of compound libraries to target EMT. Cell Death and Differentiation. doi: 10.1038/s41418-025-01515-6
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that the toxin induces DNA damage responses in cultured cells that activates a senescence tumour suppressor mechanism (https://doi.org/10.1038/s41467-019-12064-1). Cells undergoing toxin-induced senescence undergo
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Project Outline: Stroke is the second commonest cause of death and the sixth leading cause of disease burden globally with an estimated 6.5 million stroke deaths annually, expected to rise to 8
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of fibrosis, accompanied by an inappropriate immune response. It causes approximately 500,000 deaths per year and can progress to other chronic liver diseases, including cancer. Restoring homeostasis in
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MED-CORE-CARD Full Time 86632BR Job Summary The Clinical Research Coordinator (CRC) will execute, manage, and coordinate the routine duties of the POstmortem InvesTigation of Sudden Cardiac Death
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on understanding how cell death contributes to tumourigenesis using Drosophila combined with live-imaging and RNA transcriptomics. As part of this project, the candidate will be working on: 1: Labelling and live
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is underlying disease of a lower extremity arterial disease, heart attack or stroke. Lipids are of vital importance through integration in cell membranes, as energy source and in cellular signaling and
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inflammatory signals to engage anti-tumour immunity. Supervisors: Stephen Tait and Danny Huang Project summary: Cell death prevents and treats cancer. Typically, therapies cause apoptotic cell death of cancer