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; Rehill et al., Science Advances 2025). This Research Ireland-funded project will elucidate how components of the coagulation cascade modulate inflammatory cell signalling, with a view to developing novel
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fundamental level. Information on the department can be found at: https://sic.ku.dk/research/ Our research The Allergic Inflammation group at the Leo Foundation Skin Immunology Research Centre within ISIM is
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contributors to obesity and liver steatosis, where lipid accumulation becomes toxic for hepatocytes leading to cell death and consequent inflammation. Autophagy, which removes intracellular components, is key
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stem-like cell (GSC) models by sampling multiple distinct tumour regions to recapitulate their post-surgical and pre-therapy features, as well as their intra-tumoural heterogeneity (https://bit.ly
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the doctoral thesis for the 26/27 academic year. Cardiovascular diseases are the leading cause of death globally, and many of them lack effective treatment. The heart lacks sufficient capacity to repair itself
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transferable skills. Stroke remains a leading cause of death and disability worldwide, with ischemic stroke accounting for most cases. Current research often relies on animal models, such as the middle cerebral
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eukaryotic cells Leader Dr hab. Jan Paczesny Viruses are parasites with living cells as their hosts. Without cells, viruses cannot perform their life cycle. Often, viruses cause the host's death upon release
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-dependent MLCS regulation on lysosomal trafficking, mitochondrial quality control and hypoxia-induced cell death. Please apply for this project using this link: https://www.sheffield.ac.uk/postgraduate/phd
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heart failure, hypertension, atherosclerosis, stroke, aneurysms, and vascular auto-immune diseases are the most common cause of death and disability in the United States, and account for approximately 30
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, or immunodeficiencies face higher risks of infection, complications, and death. Prompt and accurate diagnosis is vital to improve outcomes in these vulnerable groups. However, clinical diagnosis of microbial infections