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to understanding the biology of healthy aging and screening for health-promoting interventions using the C. elegans genetics model. Oversees laboratory strain collection inputs and outputs with guidance from
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underpinnings of aging and the complete neuronal wiring diagrams of two sexes in the nematode C. elegans, the department has stood out through its diversity of thought, scientific questions and the experimental
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the nematode C. elegans , with an emphasis on X-chromosome dosage compensation, which balances gene expression between XX hermaphrodites and XO males, and the specification of sexual fate. Previous work by
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Instituto de Investigação e Inovação em Saúde da Universidade do Porto (i3S) | Portugal | 29 days ago
stages of organogenesis, in the spermatheca of the animal model C. elegans using genome editing and live fluorescence microscopy. Admission Requirements: Mandatory: Candidates must hold a Bsc and a
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analysis C. elegans and mouse husbandry and experimentation Data analysis using a variety of software programs, and preparation of data for presentation Training of new lab members and functional supervision
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organism C. elegans to identify new mediators of this transcription stress response. These new mediators will subsequently be functionally characterized using genetic and cell biological analysis, in
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of the machine-learning assay in other worm phenotypes. Principal Duties and Responsibilities: 50% Strain maintenance & life history analysis Maintain C. elegans strains, perform genetic crosses and characterize
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on autophagy enhancer drugs. This work has been informed by a novel C. elegans model of antitrypsin deficiency that has been adapted to high-content screening of drug and RNAi libraries for new therapies
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mechanochemically-driven cell polarization evolves. You will focus on polarization of the C. elegans one-cell embryo, which is essential for establishment of one of the main body axes. This polarization event
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are seeking motivated individual to join my research group to study the functions of DPPIV family proteases using C. elegans as a model system. Our long-term goal is to understand how these proteases regulate