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chromatin profiling methods along with CRISPR/Cas9-meduated cell line engineering and various animal models. You will study the effects of the activation or depletion of chromatin-modifying enzymes using
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: Advanced molecular and protein analysis Mass spectrometry-based imaging Multi-omics technologies Preclinical cardiometabolic animal models They will also gain professional development in data stewardship
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-energizing exhausted T cells, it is becoming apparent that many checkpoint drugs act on specific subsets of ‘stem like’ T cells, which are present in the lymph nodes, or other sites such as the tumour itself
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both sites. The project sits at the interface of cell line engineering, protein science and machine learning and you will receive advanced training in these areas while developing methods to accelerate
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are the defining and driving mediators in these two major cancer types. Since FOXA1 is the 'foundation block' of the ER and AR pathways in breast and prostate cancer, respectively, it has been an attractive drug
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neuroendocrine cancer, which is termed Neuroendocrine prostate cancer (NEPC). It is not entirely clear what replaces AR as the driver, but recent evidence has suggested that neuronal transcription factors such as
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the Department of Computer Science and Technology at the University of Cambridge. The position will be for 12 months from the 2nd February 2026 in the first instance. Project research topics must fall under
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A position exists, for a Research Assistant/Associate in the Department of Engineering, to work on experimental investigations of MILD combustion. The post holder will be located in Central
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technologies, bulk and single-cell RNA-sequencing, flow cytometry, multiplex immunofluorescence, and standard molecular biology and biochemistry techniques. A computational component may also be available
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well as academically new. Applicants should have (or expect to obtain by the start date) at least a good 2.1 degree (and preferably a Masters degree) in Engineering or Physical Sciences. Applicants should be able