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This fully-funded PhD offers a unique opportunity to drive that change. We are seeking a talented and motivated student to join a multidisciplinary team working at the intersection of biomedical
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. Like other glycans, they are not built against a defined template, and yet their structure is non-random, with specific motifs within the glycan chains defining binding sites for critical signalling and
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cultures—a powerful 3D ex vivo model—this project will dissect the mechanistic links between mTOR signalling, reactive glial phenotypes, and complement activation. The project will also incorporate human
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specific motifs within the glycan chains defining binding sites for critical signalling and structural molecules. Unravelling the ways in which these motifs are encoded into GAGs by their biosynthetic
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) offer new avenues to tackle this problem. AI models have demonstrated strong potential in clinically relevant insights from electrical signals such as ECGs, and from cardiac imaging modalities including
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) offer new avenues to tackle this problem. AI models have demonstrated strong potential in clinically relevant insights from electrical signals such as ECGs, and from cardiac imaging modalities including
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signalling, raising the possibility of shared molecular mechanisms. Project Aims This PhD project will focus on investigating the fibrotic behaviour of cells isolated from glaucoma patients of different ethnic
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Biomedical Campus. You will join an exciting research programme investigating fundamental mechanisms of ribosome assembly, translational control and how defects in these processes drive cancer development
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non-random, with specific motifs within the glycan chains defining binding sites for critical signalling and structural molecules. Unravelling the ways in which these motifs are encoded into GAGs by
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entitled Diagnostic Discard: Exploration of material values in point-of-care diagnostic sector, funded by an APEX award from the Royal Society. This research project aims to generate critical conversations