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. We will also use NMR spectroscopy to determine effects on cell metabolic pathways and secretory events in response to P2X7 stimulation. The student will gain skills in cell biology, pharmacological
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biology, and will take their newly designed and synthesised compounds into cellular models of disease. The project would particularly suit a student who has an interest in working in synthetic medicinal
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genetic adaptations (‘genetic swamping’). Training The student will receive broad training in molecular biology, historical DNA, genomics, bioinformatics and population genetics. The student will take part
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replication and transcription. Using C. elegans genetics, advanced RNA biology techniques, and industrial biochemistry training with Inspiralis Ltd., the student will investigate how RNAs and their
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recently (~50,000 years ago), there were many other types of humans on earth, including Neanderthals and Denisovans. What was it about modern human biology—if anything—that set us apart from these extinct
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to alternative splicing. This PhD offers the scope to develop independence – pursing promising leads on interesting biology – while addressing one of evolution’s most longstanding challenges. Beyond advancing
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, materials, and biomedical engineering, offering training across fabrication, nanomechanical analysis, and computational biology. It contributes to more predictive and reproducible approaches in regenerative
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College London, who is an expert in bone biology and will provide the high-resolution computed tomography (CT) scans of the bone. The overall goal of the project is to use computational approaches to map
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Pioneer the future of discovery and innovation at The University of Manchester with a fully funded Bicentenary PhD Studentship in the Faculty of Biology, Medicine and Health. The University
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integration into neural circuits to result in functional, restored behaviour. We will use the fruit-fly Drosophila as a model organism for its powerful genetics and molecular cell biology (e.g. CRISPR/Cas9 gene