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biology: Do independent mimicry rings rely on the same genes to produce colour patterns, or are there different solutions each time mimicry evolves? Research Methodology You will work with existing high
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genetic adaptations (‘genetic swamping’). Training The student will receive broad training in molecular biology, historical DNA, genomics, bioinformatics and population genetics. The student will take part
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been enhanced through predictive structural biology tools such as AlphaFold, which allow accurate prediction of effector structures from primary sequence. We recently identified a number of immune
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the student with training in diverse techniques related to molecular and cellular biology, bioinformatics and protein biochemistry. A key activity in this project will be the use of targeted reverse genetics
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metabolites. These molecules will be characterized chemically and biologically, with the aim of understanding how these molecules impact human health. This multidisciplinary project will be based in
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quality, diversity, and biological relevance using standard metrics and expert review. Anonymised digital images from tissues in biobanks will be used to train generative models on university computing
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. Approaches and goals: The overarching goal is a molecular-level understanding of this important but understudied family of molecules achieved through a multi-disciplinary approach encompassing cell biology
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: Ahola et al. Trends in Cell Biology 2024 doi: 10.1016/j.tcb.2023.06.002. Ahola et al. Cell Metabolism 2022 DOI: 10.1016/j.cmet.2022.08.017
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autophagy and the innate immunity response. Using cutting-edge omics (transcriptomics/proteomics), advanced imaging (confocal) and cellular biology approaches (macrophages, autophagy biomarkers), this project
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We seek an enthusiastic and inquisitive individual with a background in a subject aligned with the Biological Sciences, Molecular Biology, Microbiology, or Genetics. Entry Requirements At least UK