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) culture models. These findings will synergise with our spatial bioinformatic profiling of these tumour models and will be used to develop potential DDR-targeted combination therapies with as much pan-tumour
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lab https://sites.google.com/sheffield.ac.uk/lahirilab/) with structural bioinformatics (Chaudhuri lab, https://www.sheffield.ac.uk/biosciences/people/academic-staff/roy-chaudhuri) and plant genetics
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A search for pharmacological inhibitors of a cancer-associated adhesion GPCR in the zebrafish embryo
are seeking a motivated student with interests in developmental biology, disease modelling and drug discovery. This interdisciplinary project combines both wet bench work and computational work (bioinformatics
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culture of human smooth cells and isolation of human neutrophil microvesicles, confocal microscopy, flow cytometry, RNAseq, bioinformatics, ELISA, and other functional assays. You will determine whether
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genetic diversity. Projects could involve field work, experimental work, laboratory work and/or bioinformatic analysis of genomic data. You would receive training in the relevant techniques, as