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@inserm.fr Requirements Research FieldBiological sciences » Biological engineeringEducation LevelPhD or equivalent Skills/Qualifications Main responsibilities: Bioinformatics, data indexing, large-scale
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Description We are looking for a bioinformatician to join a thriving platform at the Centre d'Immunologie Marseille-Luminy (CIML) - a leading immunology research centre in Europe. You will design bioinformatics
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bioinformatics approaches to human-relevant models and unique patient-derived tissue cohorts from colorectal cancer. The aim is to dissect the tumor "ecosystem" with a particular emphasis on epithelial cells
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to the bioinformatic and computational analysis of interactions between tumors and the immune system. Using large-scale genomics approaches and single-cell technologies (scRNA-seq, scATAC-seq, scTCR-seq), it explores
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of ancient DNA, particularly in the bioinformatic analysis of data generated by high-throughput sequencing technologies applied to ancient DNA characterization and whole-genome sequencing. They demonstrate a
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at strengthening the interface between immunology, bioinformatics and gene expression regulation in a physiologic and tumor context. The analyses of genomic and transcriptomic datasets (public and internal to Curie
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and transcriptomic data that will be subjected to bioinformatic analysis to integrate and interpret complex datasets, helping us to better understand the underlying mechanisms of the disease. Our
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experiment. Finally, bioinformatics will be used to compare the sequences enriched in each experimental context (topology, addition of chemical modifications, medium composition). The most promising constructs
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. - Genome Editing by CRISPR/Cas9. - ChIP-seq/RNA-seq/ mapping of G-quadruplexes in the genome. - Large scale reporter assay. - Bioinformatics analysis. The post-doctoral fellow will join the IGMM, which is a
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pediatrics. This mission will focus primarily on the bioinformatics and genomics component of the IBSoFACTo project. The work will be carried out in collaboration with a multidisciplinary team of specialists