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the possibility of making “universal” vaccines by targeting these epitopes. We have validated this methodology for the influenza virus (https://www.nature.com/articles/s41467-018-06228-8) and the technology has
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interpret high-resolution datasets that reveal new insights into disease progression, with the ultimate aim of identifying novel biomarkers and therapeutic targets. You will hold a relevant PhD/DPhil
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that reveal new insights into disease progression, with the ultimate aim of identifying novel biomarkers and therapeutic targets. This is a unique opportunity to work at the cutting edge of translational
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approaches including targeted genetic murine models, primary cell culture and analysis, multi-omics and bioinformatics. The biological focus will be on vascular biology, immune cell function and metabolism
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in preventing immune-mediated pathology in autoimmunity remains poorly understood. Using genetic and antibody-based targeting, we aim to dissect how these pathways modulate T-cell signalling
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. By focusing on unique cell-specific receptors, outcomes will inform the development of targeted drug delivery strategies utilizing RNA therapeutics. This research will contribute to a deeper
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We are seeking a Research Assistant for a project testing the ability of phage to target bacteria carrying plasmids associated with antibiotic resistance genes. Many of the most important antibiotic
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the molecular mechanisms underlying disease progression and treatment resistance and identify novel therapeutic targets. You will take a lead on development of computational approaches to integrate multi-omics