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characterized by the degeneration of motor neurons. In 2024, after 150 years of research, the first effective gene-targeted therapies became available for patients with specific SOD1 gene mutations (<1% of all
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ALS is a rapidly progressive and fatal neurodegenerative disease characterized by the degeneration of motor neurons. In 2024, after 150 years of research, the first effective gene-targeted therapies
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5 Sep 2025 Job Information Organisation/Company Wetsus - European centre of excellence for sustainable water technology Research Field Agricultural sciences Biological sciences » Biology Researcher Profile First Stage Researcher (R1) Positions PhD Positions Country Netherlands Application...
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, and industrial partners across Europe to deliver a world-class doctoral training programme in risk assessment, resilience engineering, and smart technologies. Its scientific vision targets: (1
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for differentiating effectful programs such as gradient estimation of probabilistic programs, implicit function differentiation, compositional Bayesian inference techniques); analyzing what is required (e.g., choice
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function differentiation, compositional Bayesian inference techniques); analyzing what is required (e.g., choice of data structures, static analyses and compiler optimizations, parallelism and concurrency
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techniques (e.g., techniques for differentiating effectful programs such as gradient estimation of probabilistic programs, implicit function differentiation, compositional Bayesian inference techniques
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mathematical background, including expertise in stochastic optimization (e.g. Markov decision theory and dynamic programming) and applied probability (Bayesian statistics). Excellent coding skills (e.g., in Java
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creative – You bring substantial knowledge of statistical (e.g. Bayesian) methods, strong analytical skills, and creativity. Programming skills – You are proficient in Python and/or Matlab. Research
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using synthetic ligands that are designed to target autoreactive B cells specific to autoantigens that cannot be cellularly expressed as CAARs. In this project, funded by the ZonMW Open Competition