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-development and refinement of conceptual models; devising management scenarios; building network models in one or more platforms (e.g., loop analysis/qpress; fuzzy cognitive maps/Mental Modeler; Bayesian belief
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, to define novel biomarkers, and to identify novel therapeutical targets. We have pioneered in the integration of genetics with omic data to identify proteomic signatures and develop novel predictive models
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on recent findings on the essential target enzymes DOI: 10.1021/acs.jmedchem.5c00865. Project role includes purification of recombinant enzymes and screening inhibitors in vitro. Ideal candidates will have
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the active target and the calorimeter, employing cutting edge detector technologies (LGADs & LYSO) and fast electronics. Our team also carries a host of simulations to prototype the experiment and develop
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dementias. The ultimate goal of the NGI is to understand the biology of these diseases, to define novel biomarkers, and to identify novel therapeutic targets. WashU Medicine is renowned for its research
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target specifications of 60 Hz sampling rate and 100 m sampling length. The data for this project will come from a 3-month experiment, scheduled for November 2025 – January 2026, on the two cables
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associated events that may serve as both therapeutic targets and biomarkers for early onset dementia such as early onset Alzheimer’s disease and frontotemporal dementia. Our research leverages comprehensive
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diseases including pulmonary hypertension, and 2) identifying novel precision therapeutic approaches and targets for lung diseases and right heart failure due to pulmonary hypertension. Current research
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Position Summary The Targeted Treatments Laboratory at WashU is looking to hire a postdoctoral fellow to work on developing ultrasound-based neurostimulation devices and for applying them in
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that can facilitate timely diagnosis and inform targeted interventions for infants vulnerable to delayed language development. The successful candidate will join a collaborative, multidisciplinary team