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in preventing immune-mediated pathology in autoimmunity remains poorly understood. Using genetic and antibody-based targeting, we aim to dissect how these pathways modulate T-cell signalling
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. By focusing on unique cell-specific receptors, outcomes will inform the development of targeted drug delivery strategies utilizing RNA therapeutics. This research will contribute to a deeper
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We are seeking a Research Assistant for a project testing the ability of phage to target bacteria carrying plasmids associated with antibiotic resistance genes. Many of the most important antibiotic
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Postdoctoral Researcher to contribute to our pioneering work focused on enhancing the efficacy of radiotherapy in cancer treatment. Our research aims to develop targeted strategies that selectively increase
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the molecular mechanisms underlying disease progression and treatment resistance and identify novel therapeutic targets. You will take a lead on development of computational approaches to integrate multi-omics
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work is to identify new therapeutic targets that can inform drug development for ALS/FTD. Laboratory work will involve differentiations of human iPSCs to motor neurons, developing microfluidic and
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candidate will be a member of a large multi-disciplinary team working on UPLiFT’s Physics work package (others include the development of IFE lasers and implosion targets). At plasma conditions such as those
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to target specific transcription factors (iii) use of high content imaging and AI to phenotype these cultures (iii) use of bulk and single-cell RNAseq to characterise the transcriptional profile of each cell