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by the EPSRC SCHEMA Hub SCHEMA Hub . The research targets the preparation and properties of new plastics, thermoplastic elastomers and adhesives prepared from renewable resources and which
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human tumours. We have an exciting opportunity for a Postdoctoral Researcher to join the new team at Oxford, utilising in vivo brain tumour models to identify molecular targets underlying tumour
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their target antigens and become activated in serious human diseases, including autoimmune disorders, infectious diseases, and cancers. We study how adaptive T cell immunity is developed and/or becomes impaired
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world-leading researchers from Oxford, Harvard, and other premier institutions to develop innovative gene-silencing and gene-editing technologies targeting the underlying causes of genetic heart diseases
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to the development and implementation of strategies/action plans (and ongoing review) to ensure that targets are met according to study timelines. Supervision would be provided by senior Centre staff, including
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in preventing immune-mediated pathology in autoimmunity remains poorly understood. Using genetic and antibody-based targeting, we aim to dissect how these pathways modulate T-cell signalling
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characterising binding interactions. You will drive the completion of several mature projects to publication, including revealing new roles for disordered domains in efficient DNA target search. You may also
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renewable award. You will lead a programme of research in the molecular mechanisms of cardiovascular disease, that may include a range of approaches including targeted genetic murine models, primary cell
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culture and organoids to ensure data is clinically relevant. Our overarching aim is to utilise these techniques to identify therapeutic targets to which we can generate effective treatments. The post would
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the molecular mechanisms underlying disease progression and treatment resistance and identify novel therapeutic targets. You will take a lead on development of computational approaches to integrate multi-omics