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and in silico techniques. informatics/AI modeling approaches. identifying new therapeutic targets for chronic disease. Key responsibilities include : planning, organizing, performing, and monitoring
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proteins with regard to their role in the development of cancer, the emergence of therapy resistance, as predictive markers to guide therapy and as therapeutic targets. Your Responsibilities Independent
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-pathogenic fungi and identifies targets for the development of novel natural product-based antibiotics. The junior research group Metabolomics-guided Natural Product Discovery (https://www.leibniz-hki.de/de
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and their microenvironment, with a focus on immune cells, stromal components, and their metabolic communication. One central aim is to identify novel therapeu-tic targets for next-generation immune and
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cell populations which may involve targeted validation by working with a collaborator. Bulk tumor samples will include those of fresh-frozen material of pediatric cancer patients and archive FFPE RNA-seq
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. Recent work includes the discovery and structural characterization of novel dsDNA sensors and the identification of small molecules targeting key innate immune components https://doi.org/10.1016/j.cell
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to study hypotheses Validate models via targeted simulation, sensitivity analysis and exploration Apply methods to problems in geosciences, in particular bio-/geochemical cycles Your qualifications: A
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(SDPs). You will design climate change mitigation scenarios that respect both climate targets and sustainable development goals using the REMIND model, one of the world’s leading integrated energy-economy
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-pathogenic fungi and identifies targets for the development of novel natural product-based antibiotics. The junior research group (Epi-)Genetic Regulation of Fungal Virulence (https://www.leibniz-hki.de/en/epi
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folding, gene regulation, drug–target interactions, and multi-scale biomedical modeling. 3. Deep Learning on Graphs with Higher-Order Structures This project develops neural architectures capable