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using synthetic ligands that are designed to target autoreactive B cells specific to autoantigens that cannot be cellularly expressed as CAARs. In this project, funded by the ZonMW Open Competition
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. We aim to push the current limit of cellular therapies towards precise cellular immunotherapy using synthetic ligands that are designed to target autoreactive B cells specific to autoantigens
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PhD position understanding and designing nanomedicines-membranes interaction: physics based approach
the nanomedicines with high specificity to the desired target site in the body. In this PhD project, the candidate will experimentally study how to achieve high specificity by developing a quantitative understanding
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is to deliver the nanomedicines with high specificity to the desired target site in the body. In this PhD project, the candidate will experimentally study how to achieve high specificity by developing
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targeting mucin-degrading proteins. Selection Criteria M.Sc. degree in synthetic organic chemistry, medicinal chemistry, chemical biology or equivalent; Proven experience in synthetic organic chemistry
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synthesis of new chemical probes targeting mucin-degrading proteins. Selection Criteria M.Sc. degree in biochemistry, structural biology, chemical biology or equivalent; Proven experience with protein
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the potential of targeting host-cell metabolism to deprive intracellular bacteria of essential nutrients and boost the immune response. The candidate will work as part of an interdisciplinary team to help
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role in the Netherlands. However, given its environmental impact, the sector must be decarbonised in line with Dutch climate targets. Achieving this requires the development of innovative, transformative
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economic role in the Netherlands. However, given its environmental impact, the sector must be decarbonised in line with Dutch climate targets. Achieving this requires the development of innovative