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investigating the new pathways and targets in diabetes/obesity and cancer. The lab uses genetically engineered mouse models and molecular pharmacology tools to identify novel signaling pathways to develop new
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-free DNA (mutation and methylation), RNA, and exosomal-based liquid assays for early cancer detection, prognosis, and predictive responses to chemotherapies and targeted drugs. Studying the genetic and
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or translational research experience Knowledge of machine learning, Bayesian modeling, or statistical method development Ideal Personal Attributes: Independent, proactive, and scientifically curious Detail-oriented
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basic science with biotech applications and combines rich functional assays with cutting-edge computational biology. Our method relies on aptamer-based sensors to recognise each specific metabolite target
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cancer genes for their impact on tumorigenesis, signaling activation, and targeted therapy response (e.g., Nat Commun 2019, Nat Cell Biol 2020, Nat Commun 2024, Sci Adv 2025, Nat Genet 2025). The method
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novel in vivo gene therapy approaches targeting hematopoietic stem cells. You will generate data on efficacy and safety of gene therapy vectors in multiple target cells and carry on preclinical
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on identifying novel resistance pathways and therapeutic targets with particular attention to energy metabolism and tumor-microenvironment interactions. • Will work on primary human GBM and other cancer cell lines
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Fellowship Academy, designed to provide targeted development and support for researchers with outstanding potential, including a Fellows’ Network and bespoke mentoring. The Queen’s Global Challenges themes
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for early cancer detection, prognosis, and predictive responses to chemotherapies and targeted drugs. Studying the genetic and epigenetic basis of GI cancers (e.g., aberrant DNA methylation, histone
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well as developing new targeted therapies for hematological malignant diseases and cancers. Our research involves experiments with various biochemistry and molecular techniques, genomic approaches, and genetic and