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to identify the shared characteristics of disturbed or polluted ecosystems as well as infectious diseases on the microbiome level, and develop strategies for their remediation by targeted interventions
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of the functionalized textiles and assess their suitability for targeted applications. Collaborate with consortium partners from universities, research centres, and industry. Contribute to the preparation of scientific
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Postdoctoral Research Associate - Basic and Translational Research Training in Pediatric Classical H
by training in the execution of statistically rigorous, hypothesis-driven research that probes the mechanistic basis of hematologic disease, uncovers new therapeutic targets, and translates
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to accelerate therapeutic development for brain disorders, leveraging stem cell-derived organoid models and gene targeting tools. Our recent work demonstrated that stem cell models offer a unique opportunity to
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) investigates the pathobiology of human-pathogenic fungi and identifies targets for the development of novel natural product-based antibiotics. The research group Microbiome Dynamics (https://www.leibniz-hki.de
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models, multi-omics analyses (e.g., RNA-seq, ATAC-seq, scRNA-seq, scDNA-seq, WES/WGS, targeted NGS, DigiWest), a broad spectrum of molecular and cellular biology techniques, biochemistry and biophysics
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to study hypotheses Validate models via targeted simulation, sensitivity analysis and exploration Apply methods to problems in geosciences, in particular bio-/geochemical cycles Your qualifications: A
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malignancies. Leukemia. 2023;37(4):864-876. Kumar S, Schoonderwoerd MJA, Kroonen JS, et al. Targeting pancreatic cancer by TAK-981: a SUMOylation inhibitor that activates the immune system and blocks cancer cell
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compartments. The aim of these studies is to identify host-targeted therapies that improve clinical outcome when initiated after the onset of critical illness, when many patients present for care. Fundamental
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cell populations which may involve targeted validation by working with a collaborator. Bulk tumor samples will include those of fresh-frozen material of pediatric cancer patients and archive FFPE RNA-seq