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molecular switches that could be targeted by anti-fibrotic drugs. You will master • genome editing, • human iPSC culture and directed differentiation, • live cell biomechanical imaging, and • multiomics
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delivered in routine practice for people with alcohol and drug dependence. This will be a large-scale longitudinal cohort study using national registry data on employment and health. A target trial emulation
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Targeting Cardiometabolic Dysfunction in Heart Failure with Preserved Ejection Fraction (HFpEF): Mechanisms of Exercise-Induced Protection Overview Applications are invited for a fully funded 4-year
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mechanical fatigue—individually and sequentially, followed by electrical breakdown testing to assess their impact on the dielectric performance of the material subsystems. The target is to develop a
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target, since all known treatment resistance mechanisms are downstream of, and dependent on FOXA1. However, FOXA1 has been a difficult protein to study for technical reasons. We have developed a novel tool
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treatments that target AR have forced cancer cells to evade treatment and a newly characterised, but frequent escape mechanism is for cancer cells to lose dependence on AR and to take on features of a
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device will require an easily operable and user-friendly detection technique to identify targets of interest with minimal training or specialized equipment. The goal is to enable rapid, reliable results
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targets the development of advanced coatings to prevent cell-to-cell propagation during runaway events. It combines experimental studies, numerical modelling, and real-world burner rig testing, culminating
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explore ways to control their motion in 3D space. Synthetic microswimmers have many potential biomedical applications, including targeted drug delivery and non-invasive medical treatments. The swimmers
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ultrasound. This project will develop the materials, methods, and designs necessary to 3D-print the next generation of medical micro-robots targeting drug delivery, exploiting combinations of functions