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Field
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-climate analytics, social vulnerability modelling, and participatory engagement with local authorities, including Loughborough (UK), to co-design targeted interventions and translate findings into open
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Proteome Is Shaped by E3 Ubiquitin Ligases Targeting C-Terminal Degrons. Cell, 173 (7): 1622-1635. For more information, visit https://www.timmslab.com The successful candidate will be a highly motivated
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neuroprotective effects. Camptothecin – A clinically relevant anticancer agent targeting Topoisomerase I. In collaboration with Prozomix Ltd. (an industrial leader in enzyme development), this project will
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global temperature target, this century, can only be achieved through global net negative emissions, where CDR removes more CO2 from the atmosphere than all human activity is emitting. Today, CDR removes
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this challenge. Pathogens invade plant cells and hijack proteins that control protein synthesis, bending these processes to support pathogen growth. This project aims to target the protein-protein interactions
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that underpin immune recognition by these proteins, and how they could be engineered to expand or otherwise improve their use in agriculture. Our target for developing new disease resistance is the most
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the PhD student to propose targets to preserve liver metabolic health and prevent disease progression associated to poor dietary habits, which will be investigated in this project. This collaborative
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, alongside complex drug screening, efficacy and clinical phenotype information. Using these datasets, you will undertake comprehensive strategies aimed at the characterisation and therapeutic targeting
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interventions. These insights may ultimately lead to the identification of new targets for the development of therapies for ageing and age-related disease. For more information please contact: rebecca.c.taylor
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range of reactivity, and particularly C-C bond formation. Directed evolution approaches will then be applied to guide the selectivity of the new enzymes towards target molecules and drug fragments