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in preventing immune-mediated pathology in autoimmunity remains poorly understood. Using genetic and antibody-based targeting, we aim to dissect how these pathways modulate T-cell signalling
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gases, novel formulations for drug delivery to the skin, hair and nail, the use of skin stretching to promote needleless delivery, the use of nanomaterials in the oral and respiratory mucosa, targeting
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and electrophysiology approaches. Age-related metabolites will be targeted to improve the efficiency of generating functional hiPSC-CMs to improve therapeutic options for aged patients. The results
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precancers and developing targeted interventions, including vaccines, to intercept them. The project focuses on designing, validating, and preclinically testing neoepitope-based mRNA vaccines to prevent BRCA
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characterising binding interactions. You will drive the completion of several mature projects to publication, including revealing new roles for disordered domains in efficient DNA target search. You may also
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to the skin, hair and nail, the use of skin stretching to promote needleless delivery, the use of nanomaterials in the oral and respiratory mucosa, targeting hair follicles using nanosystems and the use of 3D
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therapeutic targets. The individual will report to the PI of the headache Group, Dr Philip R Holland and will be responsible for conducting their own independent research projects, the supervision of more
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renewable award. You will lead a programme of research in the molecular mechanisms of cardiovascular disease, that may include a range of approaches including targeted genetic murine models, primary cell
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facilely applied as a photoluminescent layer, targeting in situ detection and non-contact visualization of surface temperatures and pressures. You should hold a PhD/DPhil (or near completion*) in materials
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culture and organoids to ensure data is clinically relevant. Our overarching aim is to utilise these techniques to identify therapeutic targets to which we can generate effective treatments. The post would