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demonstrating how an existing anti-biofilm compound binds to and activates its specific target in Pseudomonas aeruginosa, we will design, develop and test novel anti-biofilm compounds with broader activity
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. The candidate will join our multi-disciplinary team and focus on the development and performance of modern assays to evaluate bioactive molecules targeting major signaling pathways in cancer and inflammation
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activates its specific target in Pseudomonas aeruginosa, we will design, develop and test novel anti-biofilm compounds with broader activity against the WHO priority pathogens Escherichia coli, Klebsiella
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steroidogenesis a critical target for chemical-induced endocrine disruption. By disturbing steroid biosynthesis EDCs are posing risks for metabolic, immune, neuronal and long-term reproductive diseases in both
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from regulators to targets in shaping the adaptive abilities of bacterial gene regulatory networks, the role of intracellular dilution is setting the sensitivity of regulatory circuitry, the dynamics