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. Among them, pore-forming proteins represent a unique class of biomolecules with the potential to be re-engineered into highly selective tools for targeting disease-relevant cells. This interdisciplinary
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uses a tumor-targeting biomolecule (e.g. antibody, peptide, small molecule) labelled with a radionuclide for either diagnostic or therapeutic purposes. Alpha-particle targeted radionuclide therapy (-TRT
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inflammation and immune response and PK dysregulation is well documented in inflammatory pathologies [8-13]. Moreover, several PKs constitute attractive pharmacological targets for therapeutic purposes, as
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, engineering, bioinformatics, machine learning, artificial intelligence) to support minimally invasive and targeted preventive and predictive medicine capable of limiting age-related functional disorders
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behaviour using computational approaches such as Bayesian program synthesis and inverse reinforcement learning. Investigate the diversity of motor commands that could implement observed behaviours and explore
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science campus. The team is composed of approximately ten members (http://ibv.unice.fr/research-team/besse/ ). Targeting of specific sets of RNA molecules to various subcellular localization has recently
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Research Institute for Environmental and Occupational Health (IRSET - UMR_S INSERM 1085) | Rennes, Bretagne | France | 7 days ago
particles - in promoting inflammation and fibrosis, and work to identify specific biomarkers of exposure and associated risks in human and mouse models. Develop and evaluate therapeutic strategies to target
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particles - in promoting inflammation and fibrosis, and work to identify specific biomarkers of exposure and associated risks in human and mouse models. Develop and evaluate therapeutic strategies to target
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producing functionalized pyoverdine, which can then be conjugated to different molecules (for example, antibiotics) to develop targeted vectors or to explore new properties of the siderophore. In this context
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convergence in the targeted generation. Other graph generative models from fields other than processes (e.g., molecular design) can be tested, provided that a simulator capable of calculating aptitudes is