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. Among them, pore-forming proteins represent a unique class of biomolecules with the potential to be re-engineered into highly selective tools for targeting disease-relevant cells. This interdisciplinary
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uses a tumor-targeting biomolecule (e.g. antibody, peptide, small molecule) labelled with a radionuclide for either diagnostic or therapeutic purposes. Alpha-particle targeted radionuclide therapy (-TRT
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inflammation and immune response and PK dysregulation is well documented in inflammatory pathologies [8-13]. Moreover, several PKs constitute attractive pharmacological targets for therapeutic purposes, as
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, engineering, bioinformatics, machine learning, artificial intelligence) to support minimally invasive and targeted preventive and predictive medicine capable of limiting age-related functional disorders
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behaviour using computational approaches such as Bayesian program synthesis and inverse reinforcement learning. Investigate the diversity of motor commands that could implement observed behaviours and explore
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producing functionalized pyoverdine, which can then be conjugated to different molecules (for example, antibiotics) to develop targeted vectors or to explore new properties of the siderophore. In this context
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convergence in the targeted generation. Other graph generative models from fields other than processes (e.g., molecular design) can be tested, provided that a simulator capable of calculating aptitudes is
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) capture and degradation for a wide range of target molecules, (iii) while guaranteeing excellent compatibility with many synthetic or natural textile fibres to maintain their intrinsic properties
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Institut de chimie des milieux et matériaux de Poitiers - Equipe SAMCat | Poitiers, Poitou Charentes | France | 5 days ago
. The candidate will conduct research within both entities. This doctoral project will be supported by a CIFRE funding application currently under review at ANRT. Objectives Characterize different forms of target
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the development of climate models to meet societal expectations for climate action, particularly in the area of adaptation to future climate change. The program is structured into 10 targeted projects and one