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. Among them, pore-forming proteins represent a unique class of biomolecules with the potential to be re-engineered into highly selective tools for targeting disease-relevant cells. This interdisciplinary
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uses a tumor-targeting biomolecule (e.g. antibody, peptide, small molecule) labelled with a radionuclide for either diagnostic or therapeutic purposes. Alpha-particle targeted radionuclide therapy (-TRT
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, engineering, bioinformatics, machine learning, artificial intelligence) to support minimally invasive and targeted preventive and predictive medicine capable of limiting age-related functional disorders
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inflammation and immune response and PK dysregulation is well documented in inflammatory pathologies [8-13]. Moreover, several PKs constitute attractive pharmacological targets for therapeutic purposes, as
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English. The candidate will have access to all the team's equipment, the shared IGH facilities, and the Biocampus platforms. Targeting meiotic DNA breaks to the right place at the right time Meiosis is the
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science campus. The team is composed of approximately ten members (http://ibv.unice.fr/research-team/besse/ ). Targeting of specific sets of RNA molecules to various subcellular localization has recently
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genes, thereby increasing their prevalence within a population. This approach can be used to disseminate a genetic modification through a target species, with the potential to control or eliminate
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producing functionalized pyoverdine, which can then be conjugated to different molecules (for example, antibiotics) to develop targeted vectors or to explore new properties of the siderophore. In this context
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convergence in the targeted generation. Other graph generative models from fields other than processes (e.g., molecular design) can be tested, provided that a simulator capable of calculating aptitudes is
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) capture and degradation for a wide range of target molecules, (iii) while guaranteeing excellent compatibility with many synthetic or natural textile fibres to maintain their intrinsic properties