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biochemical reconstitution, electron cryomicroscopy (cryo-EM), advanced bacterial genetics, and phage biology to explore how cells and viruses control the three-dimensional structure of DNA. We investigate how
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at the Department of Biochemistry. You will be working on a project that will study the functional importance and prevalence of filamentation among transcription factors at the structural level. The project has a
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relevant skills acquired and will also be determined by the funding available. About you Applicants will hold a PhD/DPhil or be near completion of a PhD/DPhil in a subject relative to Structural Biology
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in Mass Spectrometry and Structural Glycobiology to work under the supervision of Prof. Weston Struwe for a period of 24 months. The project, funded by the UKRI, centres on developing advanced methods
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methodology, theory, and applications across the areas of Bayesian experimental design, active learning, probabilistic deep learning, and related topics. The £1.23M project is funded by the UKRI Horizon
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inhibitors and bifunctional molecules Experience in using structural guidance for ligand design Experience in cell viability and lysis assays, fluorescent reporter assays, flow cytometry, CETSA, ELISA, Western
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Postdoctoral Research Associate in Sum-Frequency Generation Microscopy of Biomolecular Self-Assembly
the institute focusses on the structure and dynamics of elementary processes in solids and at surfaces. Within this broader research theme, the Nonlinear Chemical Imaging (NCI) group of Dr. Alexander Fellows
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generate key structural and biophysical data to support the design of small molecule inhibitors with particular focus on protein production and crystallisation, solving protein-ligand structures, fragment
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Prevention Initiative (COPI). The successful applicant will develop the simulation model capabilities using the PRIMEtime structure to estimate the impacts of the suite of interventions being implemented in
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for carrying out research to develop iPSC-derived lung cell models. Working within a team of biochemists, cell and structural biologists, you will perform experimental work to apply omics technologies, advanced