8 augmented-workers-using-smart-robats-in-manufacturing-cell PhD positions at International PhD Programme (IPP) Mainz in Germany
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or Th17 immune responses. Recent advances in single cell profiling have identified additional Dendritic cell populations, including transitional tDC and type 3 Dendritic cells. Yet, their functional role in
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now allow us to study physically interacting cells to define a temporal interactome. In this PhD project, developing these tools in in vitro explants, in vivo models and patient samples of type 2 immune
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associated with cancer and neurodegenerative diseases. We have developed an unbiased mass spectrometry-based proteomics approach to identify proteins that regulate R-loops in human cells and discovered a role
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. Epitranscriptomics is a new science field that studies RNA modifications (epitranscriptomic marks) and their function in regulation of gene expression. It is long known that many different RNA modifications exist. Yet
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. Validation of these candidates will be carried out through the employment of the various mouse models of accelerated senescence in stromal cells or accelerated aging of the hematopoietic system, available in
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discriminated against all other nuclear RNAs? How does the cell ensure that only fully matured mRNAs are exported? How are faulty mRNAs and transcription byproducts targeted for degradation? At the core of mRNA
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genome stability, chromosomal integrity, and cellular function. Transcription-coupled nucleotide excision repair (TC-NER) defects can cause growth and mental retardation, photosensitivity, and premature
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interaction interfaces. The PhD candidate will work on substantial improvements of these existing computational pipelines and use them subsequently to discover novel modes of protein-protein binding by