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. However, upon aging, HSC become dysfunctional and show differentiation imbalances toward an increased production of myeloid cells at the expenses of the adaptive immune lymphocytes. This has been associated
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activate CD8 T cell responses, Langerhans Cells are associated with Tolerance and homeostasis, plasmacytoid DC contribute to the defense against viruses, while type 2 dendritic cells drive CD4+ T helper cell
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developmental impact of these paralogous variants remain underexplored, particularly in humans, where further diversifications have occurred. This project will investigate how chromatin-associated paralogues
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macrophase separation, leading to visible “protein/RNA” droplets, has been widely studied and suggested to be a mechanism underlying so-called membraneless organelles, potential associative mechanisms
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of the Leibniz Association. The following position is to be filled at the institute at the earliest possible date, for a fixed term of three years, as part of the Leibniz Association funded project
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or dysfunction of these ion channels is associated with various diseases such as lysosomal storage disorders, cardiac arrhythmias and heart failure. Further information can be found on our homepage . The BMC is
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)). Intriguingly, many of these conditions are also associated with R-loop accumulation, raising the possibility that Polθ may play a direct role in repairing R-loop-induced damage. This study, conducted in
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associated pollutants in the soil? References: Vockenberg,T., Wichard, T., Ueberschaar, N., Franke M., Stelter, M., Braeutigam, P., The sorption behaviour of amine micropollutants on polyethylene microplastics
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of the Leibniz Association. The following position is available at the Institute subject to approval by the funding organization from October 1, 2025, for a fixed term of three years, in the program
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institutes in Berlin which are funded by the federal and state governments. The research institutes belong to the Leibniz Association. WIAS invites applications as PhD Student Position (f/m/d) (Ref. 25/11) in